Hey Tandy, welcome back!
Any idea what the issue is?
When you press the push-to-talk button, does the "TX" light up? If so, double-check that you have the correct input device selected in vPilot, and also that you're within "range" of the controller. If you're too far away, they may not hear you.
If the "TX" does NOT light up, could be that you need to check your settings (PTT key and/or mic device).
In either case, you should always run vPilot "as administrator" so it can always "see" your PTT.